Isotonix® Heart Health Advanced LipiTrim® Ultra

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• Antioxidant
• Helps promote delivery of healthy levels of LDL throughout the body
• Promotes a normal rate of cholesterol production
• Helps maintain healthy levels of total cholesterol, LDL cholesterol and triglyceride levels
• Supports normal synthesis of triglycerides in the liver

Sytrinol® 300 mg (Polymethoxylated Flavones, Palm Tocotrienols)
Sytrinol is a patented proprietary formula derived from natural citrus polymethoxylated flavones (PMFs) and palm tocotrienols. This combination results in a synergistic effect for helping to maintain healthy cholesterol, LDL cholesterol and triglyceride levels. Sytrinol has also been shown to help maintain healthy HDL levels. Sytrinol is a powerful antioxidant with numerous heart health benefits.  It promotes cardiovascular health, supports glycemic control and promotes normal blood platelet aggregation.

Polymethoxylated Flavones (PMFs)
Polymethoxylated Flavones are extremely bioactive potent bioflavonoids found in citrus fruits. This is especially true for tangeretin and nobiletin, two of the most common flavonoids found in nutrient-rich foods. More than 25 years of documented research provides evidence that these particular bioflavonoids deliver heart health benefits. Specific PMFs, including nobiletin and tangeretin, have been found to help maintain normal levels of LDL cholesterol.  Apolipoprotein B is considered the primary building block of LDL, making up almost 90 percent of the LDL cholesterol complex. Triglycerides are one of the key contributors to the formation of apolipoprotein B.

In vitro, Sytrinol was shown to help maintain normal cytokine activity; cytokines such as interleukin-6 and interleukins 1-beta. Sytrinol was also shown to promote normal t-lymphocyte mitogenic response and thymidine uptake by activated lymphocytes.

Palm Tocotrienols
Palm tocotrienols, along with tocopherols, are members of the Vitamin E family and are extracted from the fruit of the palm tree. Like Vitamin E, palm tocotrienols help maintain a healthy level of HMG-CoA reductase, a key enzyme in our bodies used by the liver to produce cholesterol.  New data on the biological activity of tocotrienols in cardiovascular health maintenance, along with its antioxidant properties, have raised tocotrienols to a new level of prominence in the scientific community.

A completely new perspective has developed into the role tocotrienols play in heart health and their importance as a supplement to a healthy diet. Some of the key areas of interest have centered on its role in maintaining and support a healthy cardiovascular system by helping to maintain healthy cholesterol levels and supporting healthy blood platelet activity. In a recent study that was published in the Journal of Atherosclerosis, researchers at the Kyoto Prefectural University of Medicine in Japan found that tocotrienols were more effective than Vitamin E in promoting heart health.  The study revealed that tocotrienols accumulate at levels that are 25-95 times greater than alpha tocopherol in human aortic endothelial cells.

Tocotrienols are also potent antioxidants. In human studies, researchers observed that alpha tocotrienols reduced the oxidation of LDL. The antioxidant properties of tocotrienols can mitigate the damage caused by free radicals while protecting cell membranes for better cellular communication.

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A clinical trial consisting of 60 adults showed that four weeks of treatment with 300 mg of patented Sytrinol daily promoted normal levels of total cholesterol, LDL cholesterol and triglycerides.  Follow up clinical studies have provided further support that Sytrinol promotes cardiovascular health.

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Poor cardiovascular health is one of the leading causes of death and illness in the United States, accounting for one out of every two deaths in both men and women. Poor cardiovascular health is becoming a worldwide epidemic. An unhealthy diet of processed, high-calorie, high-fat foods, pollution, smoking and sedentary lifestyles all contribute to poor heart health. Not smoking, maintaining a healthy weight, eating a diet rich in fruits, vegetables and whole grains, exercising regularly and taking the right supplements can all contribute to promoting cardiovascular health. Synthesis of cholesterol in the liver and other cells in the body is responsible for about 70 percent of our total cholesterol, with the other 30 percent from food. Maintaining healthy cholesterol and triglyceride levels is important to the overall health of the cardiovascular system.

Cholesterol is a soft, fat-like, waxy substance found in the bloodstream and in all your body’s cells. It is normal to have cholesterol. Cholesterol is an important part of a healthy body because it is used for producing cell membranes and some hormones, and serves other needed bodily functions. Cholesterol cannot dissolve in the blood. It has to be transported to and from the cells by carriers called lipoproteins. Low-density lipoprotein, or LDL, is known as “bad” cholesterol. High-density lipoprotein, or HDL, is known as “good” cholesterol. Triglycerides are a form of fat made in the body.

Cholesterol comes from two sources, the body and food. The liver and other cells in the body make about 70 percent of blood cholesterol. The other 25 percent comes from food. The body produces LDL cholesterol (bad cholesterol) naturally, but many people inherit genes from their family that cause their body to create excess amounts of cholesterol. Eating saturated fat, trans fats and dietary cholesterol also increase the overall amount of cholesterol in the blood. Because high cholesterol levels can be dangerous, it is important to maintain healthy levels of cholesterol, both the good and the bad, in the body.

Heart Health™ Advanced LipiTrim® Ultra is composed of Sytrinol®, a patented proprietary formula derived from natural citrus polymethoxylated flavones (PMFs) and palm tocotrienols, designed to promote overall cardiovascular health. Sytrinol works in the liver, without inhibiting the production of CoQ10. Advanced LipiTrim Ultra is a powerful antioxidant; it helps promote delivery of healthy levels of LDL throughout the body, promotes a normal rate of cholesterol production, helps maintain healthy levels of total cholesterol, LDL cholesterol and triglyceride levels, and promotes the normal synthesis of triglycerides in the liver.*

What does lifestyle have to do with maintaining a healthy heart?
There are simple, everyday things you can do to help maintain proper heart heath.  Among these are:

• Not smoking
• Maintaining a healthy height-to-weight ratio
• Eating a diet rich in fruits, vegetable and whole grains
• Limiting the consumption of total and saturated fat
• Exercising regularly
• Working with your physician to monitor cholesterol, blood pressure, homocysteine and C-reactive protein levels
• Starting a complete nutritional supplementation program designed to help maintain proper cardiovascular health

Why is LDL cholesterol considered bad?
When too much LDL cholesterol circulates in the blood, it can slowly build up in the inner walls of the arteries that feed the heart and brain. Together with other substances it can form plaque, a thick, hard deposit that can clog those arteries. If a clot forms and blocks a narrowed artery, it can cause serious heart problems.

Why is HDL cholesterol considered good?
About one-third to one-fourth of blood cholesterol is carried by high-density lipoprotein (HDL). HDL cholesterol is known as the good cholesterol because a high level of it seems to protect against heart problems. Medical experts think that HDL tends to carry cholesterol away from the arteries and back to the liver, where it’s passed from the body. Some experts believe that HDL removes excess cholesterol from plaque in arteries, thus slowing the buildup.

What are triglycerides, and how are they related to HDL and LDL?
A triglyceride is a form of fat. It comes from food and is also made in your body. People with high triglyceride levels often have high overall cholesterol, which is high LDL and low HDL cholesterol levels.

* These statements have not been evaluated by the Food and Drug Administration.
This product(s) is not intended to diagnose, treat, cure or prevent any disease.